After selecting a series episode on Amazon Prime, and skipping the teaser, I got a frozen screen from the teaser, with subtitles popping up on it. I have selected subtitles "off".
Cured by going back to streaming services screen, re-selecting Amazon Prime, then the series, then the episode.
Episodes are still failing to load on the first try, with up to 4 attempts required to get an episode to play.
Once running, the episodes play without any issue.